Bocas del Toro
Besides the bars and restaurants, there are fitness classes, Spanish classes, dive lessons, Catamaran tours, Live music venues, the beaches, volunteer opportunities and just meeting people walking down the street.
Besides the multicultural Panamanians there are people from all over the world here and seven different Indian tribes. For the most part everyone gets along great. There are occasional clashes in any community and this is a tight knit one where people help their neighbors. Panama welcomes people from many countries with great expat laws and easy residency
The main industry is tourism and there are more hotels, B&B's, hostels, bars and restaurants popping up all the time. There is a growing service industry as Expat move here and create demand for services. If you get a work visa you can be hired legally but many people work with out them. it is also relatively easy to start your own business. It helps to live here for a while to learn the ropes.
I would echo what the person who did the review on Boquete. Embrace the local culture and ways of doing things. Don't come here wanting to change the way folks have done things for a long time or try to make it like the US. At the same time you can teach the locals what you know in a nice way as you make friends with them.